Expert Profile
Rod MacKinnon, M.D.
Nobel Laureate · Professor of Molecular Neurobiology and Biophysics
Background
About Rod MacKinnon
Rod MacKinnon, M.D., is a biophysicist and neuroscientist, the John D. Rockefeller Jr. Professor and head of the Laboratory of Molecular Neurobiology and Biophysics at The Rockefeller University, and an Investigator of the Howard Hughes Medical Institute. He shared the 2003 Nobel Prize in Chemistry with Peter Agre for structural and mechanistic studies of ion channels. In 1998 his team determined the first three-dimensional structure of a potassium channel by X-ray crystallography, showing how these channels conduct potassium ions rapidly while excluding sodium. His laboratory has since solved structures of voltage-dependent and ligand-regulated channels and studies how voltage, cell signals and mechanical force open and close them. Dr. MacKinnon is a co-founder of Flex Pharma.
Dr. MacKinnon earned his B.A. in Biochemistry from Brandeis University (1978) and his M.D. from Tufts University School of Medicine (1982). He served on the faculty of Harvard Medical School from 1989 to 1996 before moving to Rockefeller, and his honors include the Albert Lasker Basic Medical Research Award (1999).
